LUCY one-year results presented at SVS

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Ovation graft and delivery system

One-year results from the LUCY (Evaluation of females who are underrepresented candidates for abdominal aortic aneurysm repair) registry were reported at the Society for Vascular Surgery Annual Meeting (SVS; 20–23 June, Boston, USA). The LUCY study is the first to prospectively evaluate endovascular aneurysm repair (EVAR) outcomes in women who have more complex aortic anatomy and, subsequently, have worse reported outcomes than men undergoing EVAR.

The LUCY one-year data expand on the 30-day results presented last year, showing that at least 28% more women are eligible for minimally-invasive EVAR when using the Ovation Abdominal Stent Graft System (Endologix) than when using other EVAR systems.

The LUCY study is a prospective, consecutively enrolling, non-randomised, multicentre, post-market registry evaluating the Ovation System for the endovascular treatment of abdominal aortic aneurysms (AAA) in women. The study enrolled a total of 225 patients, including 76 females in the treatment group and 149 males in the control group, at 39 sites in the USA. The primary endpoint of the study was the 30-day major adverse event rate and secondary endpoints included serious and non-serious adverse events through one year.

The one-year LUCY data showed that, despite having more complex anatomy at the time of the index procedure than men, women had similar outcomes to men following treatment with the ultra-low profile (14F) Ovation device:

• Freedom from AAA-related morality: 100% in women vs 98.6% in men
• Freedom from reintervention for Type 1a endoleak: 98.6% in women vs 97.9% in men
• Freedom from rupture: 100% in both women and men
• Freedom from conversion: 100% in both women and men
• Freedom from all device-related reintervention: 97.2% in both women and men

Jennifer Ash, Christie Clinic Vein and Vascular Center and Assistant Clinical Professor of Surgery, University of Illinois College of Medicine in Champaign, USA, said, “Women have specific anatomical challenges in iliac access and proximal aortic neck morphology and have historically had worse outcomes from EVAR than men. The results of the LUCY study suggest that the unique features of the low-profile Ovation system may overcome these challenges and achieve similar outcomes in men and women.”

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