Randomised controlled trial of anti-microbial agents for the treatment of venous leg ulcers

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No significant difference between silver-donating and low-adherent dressings was found in a trial 213 patients (107 randomised to silver, 106 to low-adherent control), presented at the Vascular Society of Great Britain and Ireland meeting. Ulcer healing was assessed at 12 weeks, six months and one year. Out to one year, silver-donating dressings showed a 96% healing rate and low-adherent dressings 95.7%, leading investigators to conclude that there were no significant differences in efficacy between the two dressings. They added however, that silver-donating dressings cost significantly more, with an average of £95.85 per patient.

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