In this supplement: -SAFEPAX: No drug coating pitfalls -Why the RAPID trial is of clinical importance for a paradigm shift -Vascular access rescue with the APERTO Shunt DCB -The RAPID randomised controlled trial clinical results -LEGFLOW: The next-generation peripheral DCB -MAGNIFICENT: A multicentre randomised trial of LEGFLOW DCB vs. POBA -The LEG-DEB study results